Layer by Layer Three-dimensional Tissue Epitaxy by Cell-Laden Hydrogel Droplets
نویسندگان
چکیده
منابع مشابه
Layer by layer three-dimensional tissue epitaxy by cell-laden hydrogel droplets.
The ability to bioengineer three-dimensional (3D) tissues is a potentially powerful approach to treat diverse diseases such as cancer, loss of tissue function, or organ failure. Traditional tissue engineering methods, however, face challenges in fabricating 3D tissue constructs that resemble the native tissue microvasculature and microarchitectures. We have developed a bioprinter that can be us...
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For tissue engineering applications, scaffolds should be porous to enable rapid nutrient and oxygen transfer while providing a three-dimensional (3D) microenvironment for the encapsulated cells. This dual characteristic can be achieved by fabrication of porous hydrogels that contain encapsulated cells. In this work, we developed a simple method that allows cell encapsulation and pore generation...
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Alginate hydrogel is a popular biologically inert material that is widely used in 3D bioprinting, especially in extrusion-based printing. However, the printed cells in this hydrogel could not degrade the surrounding alginate gel matrix, causing them to remain in a poorly proliferating and non-differentiating state. Here, we report a novel study of the 3D printing of human corneal epithelial cel...
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ژورنال
عنوان ژورنال: Tissue Engineering Part C: Methods
سال: 2010
ISSN: 1937-3384,1937-3392
DOI: 10.1089/ten.tec.2009.0179